Potent and Powerful
Methotrexate (MTX) is an antifolate therapeutic agent that possesses potent anticancer activity against both solid tumors and leukemia.
High-dose methotrexate (HDMTX), defined as a dose higher than 500 mg/m2, is used to treat a range of adult and childhood cancers, including:
- Adult acute lymphoblastic leukemia (ALL)
- Pediatric acute lymphoblastic leukemia (ALL) • Primary CNS lymphoma
- Primary CNS lymphoma